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1-Methylpiperazine

1-Methylpiperazine

Anfon ymchwiliad

Cyflwyniad Cynnyrch

1-Gwybodaeth sylfaenol Methylpiperazine
Enw Cynnyrch: 1-Methylpiperazine
Cyfystyron: N-METHYLPIPERAZINE;NMPRZ;1-methyl-piperazin;1-METHYLPIPERAZINE AR GYFER SYNTHESIS; Cyfansoddyn Cysylltiedig â Seiclon A;N-Methyl piperazine;4-Methylpiperazine;1-Methylpiperazine, 99+% 100GR
CAS: 109-01-3
MF: C5H12N2
MW: 100.16
EINECS: 203-639-5
Categorïau Cynnyrch: 1; Benzotriazoles, Triasolau; Blociau Adeiladu; C4 i C8; Synthesis Cemegol; Blociau Adeiladu Heterocyclic; Nitrogen sy'n cynnwys; Trefnu Alffa; Heterocyclics; M; malphabetig; META - Dosbarth METHCemegol; Anweddol / Lled-folatig; Blociau Adeiladu Heterocyclic; Blociau Adeiladau Pibellau; ;Piperazine;Piperazine yn deillio;Piperazines;Blociau Adeiladu
Ffeil Mol: 109-01-3.mol
1-Methylpiperazine Structure
 
1-Priodweddau Cemegol Methylpiperazine
Ymdoddbwynt -6 gradd
berwbwynt 138 gradd (g.)
dwysedd 0.903 g/mL ar 25 gradd (goleu.)
dwysedd anwedd 3.5 (vs aer)
pwysedd anwedd 12 hPa (20 gradd)
mynegai plygiannol n20/D 1.466 (g.)
Fp 108 gradd F
tymheredd storio. 2-8 gradd
hydoddedd Clorofform (Toddadwy), Methanol (Toddadwy)
pka pK1:4.94(+2);pK2:9.09(+1) (25 gradd ,μ=0.1)
ffurf Hylif
Disgyrchiant Penodol 0.903
lliw Clir
PH 11-12 (50g/l, H2O, 20 gradd)
terfyn ffrwydrol 1.2-9.9%(V)
Hydoddedd Dŵr hydawdd
Sensitif Hygrosgopig
BRN 102724
InChIKey PVOAHINGSUIXLS-UHFFFAOYSA-N
LogP -0.57 ar 25 gradd
Cyfeirnod Cronfa Ddata CAS 109-01-3(Cyfeirnod Cronfa Ddata CAS)
Cyfeirnod Cemeg NIST Piperazine, 1-methyl-(109-01-3)
System Cofrestrfa Sylweddau EPA Piperazine, 1-methyl- (109-01-3)
 
Gwybodaeth Diogelwch
Codau Perygl T,F,C,Xi
Datganiadau Risg 10-21-23-34-36/37/38-20/21
Datganiadau Diogelwch 16-26-36/37/39-45-36
RIDADR Cenhedloedd Unedig 2734 8/PG 2
WGK yr Almaen 2
RTECS TM1225000
Tymheredd Autoignition 320 gradd
Nodyn Perygl Fflamadwy / Gwenwynig / Cyrydol / Storio o dan nitrogen
TSCA Oes
Dosbarth Perygl 3
PacioGrŵp III
Cod HS 29335995
Gwenwyndra LD50 ar lafar mewn Cwningen: 2547 mg/kg LD50 Cwningen ddermol 1341 mg/kg
 
Gwybodaeth MSDS
Darparwr Iaith
1-Methylpiperazine Saesneg
ACROS Saesneg
SigmaAldrich Saesneg
ALFA Saesneg
 
1-Defnydd a Synthesis Methylpiperazine
Priodweddau Cemegol hylif clir
Defnyddiau 1-Defnyddir Methylpiperazine wrth baratoi 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP)
Defnyddiau 1-Defnyddir methylpiperazine wrth baratoi 2-(4-methyl-1-piperazinylmethyl)acrylophenone. Mae'n ymwneud â pharatoi 1-(4-methoxy-phenyl)-4-methyl-piperazine drwy adweithio â 1-chloro-4-methoxy-bensen. Mae'n gweithredu fel canolradd yn y synthesis o gynhwysion fferyllol gweithredol fel ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine a zopiclone. Ymhellach, fe'i defnyddir fel templed dynwared wrth baratoi microsfferau wedi'u hargraffu'n foleciwlaidd. Yn ogystal â hyn, fe'i defnyddir i gynhyrchu cyfnod sefydlog cyfnewid anion cryf anweithredol o ddeilliad 1,{{2-diazacyclohexane.
Diffiniad ChEBI: 1-N-methylpiperazine yw Methylpiperazine.
Perygl Risg gymedrol o dân.
Fflamadwyedd a Hyblygrwydd fflamadwy
Proffil Diogelwch Gwenwyn trwy lwybr mewnperitoneol. Cymedrol wenwynig trwy anadliad, llyncu, a chyswllt croen. Llid difrifol ar y croen a'r llygaid. Hylif fflamadwy pan fydd yn agored i wres neu fflam; yn gallu adweithio â deunyddiau ocsideiddiol. I ymladd tân, defnyddiwch ewyn alcohol, CO2, cemegol sych. Pan gaiff ei gynhesu i ddadelfennu mae'n allyrru mygdarthau gwenwynig o NOx.
 
1-Cynhyrchion Paratoi Methylpiperazine A Deunyddiau Crai
Deunyddiau crai Methanol-->Carbon dioxide-->Piperazine-->PIPERAZINE HEXAHYDRATE-->PIPERAZINE DIHYDROCHLORIDE
Cynhyrchion Paratoi Zopiclone-->2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbaldehyde-->3-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZALDEHYDE-->2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxamide-->2-(4-Methylpiperazin-1-yl)pyrimidin-5-amine-->(2-(4-Methylpiperazin-1-yl)pyrimidin-5-yl)methanol-->2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonyl chloride-->(3,4-DIAMINO-PHENYL)-(4-METHYL-PIPERAZIN-1-YL)-METHANONE-->2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxylic acid-->2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonitrile-->3-(4-Methylpiperazin-1-ylmethyl)benzoic acid-->Ethyl 2-(4-methylpiperazin-1-yl)pyrimidine-5-carboxylate-->4-[(4-Methylpiperazin-1-yl)methyl]aniline-->(2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanamine-->CHLORCYCLIZINE HYDROCHLORIDE-->2-Hydrazinyl-1-(4-methylpiperazin-1-yl)ethanone-->3-Hydrazinyl-1-(4-methylpiperazin-1-yl)propan-1-one-->CHLORCYCLIZINE-->2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbaldehyde-->Levofloxacin-->2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide-->(2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanol-->2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-amine-->2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbonitrile-->4-(4-Methylpiperazino)aniline-->2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylic acid-->1-METHYL-4-(4-NITROPHENYL)PIPERAZINE-->Ethyl 2-(4-methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate-->4-(4-METHYLPIPERAZINOMETHYL)BENZOIC ACID-->(4-METHYL-PIPERAZIN-1-YL)-ACETIC ACID-->Clozapine-->1-METHYL-4-(3-NITROPHENYL)PIPERAZINE-->1-AdaMantanethylaMine-->1-METHYL-4-(4-NITROBENZYL)PIPERAZINE-->1-Amino-4-methylpiperazine-->1-FORMYL-4-METHYLPIPERAZINE

Tagiau poblogaidd: 1-methylpiperazine, Tsieina 1-gweithgynhyrchwyr methylpiperazine, cyflenwyr, ffatri

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